Murray State NCAA Tournament Results
Tournament Record: 2 - 14
Current Conference: Ohio Valley
| Year | Seed | Record | Finishing Round | Coach |
| 1964 | - | 0 - 1 | Round of 32 (1st rd) | Cal Luther |
| 1969 | - | 0 - 1 | Round of 32 (1st rd) | Cal Luther |
| 1988 | 14 | 1 - 1 | Round of 32 (2nd rd) | Steve Newton |
| 1990 | 16 | 0 - 1 | Round of 64 (1st rd) | Steve Newton |
| 1991 | 13 | 0 - 1 | Round of 64 (1st rd) | Steve Newton |
| 1992 | 14 | 0 - 1 | Round of 64 (1st rd) | Scott Edgar |
| 1995 | 15 | 0 - 1 | Round of 64 (1st rd) | Scott Edgar |
| 1997 | 15 | 0 - 1 | Round of 64 (1st rd) | Mark Gottfried |
| 1998 | 9 | 0 - 1 | Round of 64 (1st rd) | Mark Gottfried |
| 1999 | 13 | 0 - 1 | Round of 64 (1st rd) | Tevester Anderson |
| 2002 | 14 | 0 - 1 | Round of 64 (1st rd) | Tevester Anderson |
| 2004 | 12 | 0 - 1 | Round of 64 (1st rd) | Mick Cronin |
| 2006 | 14 | 0 - 1 | Round of 64 (1st rd) | Mick Cronin |
| 2010 | 13 | 1 - 1 | Round of 32 (2nd rd) | Billy Kennedy |
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