Iowa State NCAA Tournament Results
Tournament Record: 12 - 13
Current Conference: Big Twelve
| Year | Seed | Record | Finishing Round | Coach |
| 1944 | - | 1 - 1 | National Semifinals (2nd rd) | Louis Menze |
| 1985 | 13 | 0 - 1 | Round of 64 (1st rd) | Johnny Orr |
| 1986 | 7 | 2 - 1 | Sweet Sixteen (3rd rd) | Johnny Orr |
| 1988 | 12 | 0 - 1 | Round of 64 (1st rd) | Johnny Orr |
| 1989 | 10 | 0 - 1 | Round of 64 (1st rd) | Johnny Orr |
| 1992 | 10 | 1 - 1 | Round of 32 (2nd rd) | Johnny Orr |
| 1993 | 8 | 0 - 1 | Round of 64 (1st rd) | Johnny Orr |
| 1995 | 7 | 1 - 1 | Round of 32 (2nd rd) | Tim Floyd |
| 1996 | 5 | 1 - 1 | Round of 32 (2nd rd) | Tim Floyd |
| 1997 | 6 | 2 - 1 | Sweet Sixteen (3rd rd) | Tim Floyd |
| 2000 | 2 | 3 - 1 | Elite Eight (4th rd) | Larry Eustachy |
| 2001 | 2 | 0 - 1 | Round of 64 (1st rd) | Larry Eustachy |
| 2005 | 9 | 1 - 1 | Round of 32 (2nd rd) | Wayne Morgan |
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