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| also: | Great Midwest Independent Metro Missouri Valley |
| Year | Seed | Record | Finishing Round | Coach |
| 1958 | - | 1 - 1 | Sweet Sixteen (2nd rd) | George Smith |
| 1959 | - | 3 - 1 | National Semifinals (4th rd) | George Smith |
| 1960 | - | 3 - 1 | National Semifinals (4th rd) | George Smith |
| 1961 | - | 4 - 0 | National Championship (5th rd) | Ed Jucker |
| 1962 | - | 4 - 0 | National Championship (5th rd) | Ed Jucker |
| 1963 | - | 3 - 1 | National Championship (5th rd) | Ed Jucker |
| 1966 | - | 0 - 2 | Sweet Sixteen (2nd rd) | Tay Baker |
| 1975 | - | 2 - 1 | Sweet Sixteen (2nd rd) | Gale Catlett |
| 1976 | - | 0 - 1 | Round of 32 (1st rd) | Gale Catlett |
| 1977 | - | 0 - 1 | Round of 32 (1st rd) | Gale Catlett |
| 1992 | 4 | 4 - 1 | National Semifinals (5th rd) | Bob Huggins |
| 1993 | 2 | 3 - 1 | Elite Eight (4th rd) | Bob Huggins |
| 1994 | 8 | 0 - 1 | Round of 64 (1st rd) | Bob Huggins |
| 1995 | 7 | 1 - 1 | Round of 32 (2nd rd) | Bob Huggins |
| 1996 | 2 | 3 - 1 | Elite Eight (4th rd) | Bob Huggins |
| 1997 | 3 | 1 - 1 | Round of 32 (2nd rd) | Bob Huggins |
| 1998 | 2 | 1 - 1 | Round of 32 (2nd rd) | Bob Huggins |
| 1999 | 3 | 1 - 1 | Round of 32 (2nd rd) | Bob Huggins |
| 2000 | 2 | 1 - 1 | Round of 32 (2nd rd) | Bob Huggins |
| 2001 | 5 | 2 - 1 | Sweet Sixteen (3rd rd) | Bob Huggins |
| 2002 | 1 | 1 - 1 | Round of 32 (2nd rd) | Bob Huggins |
| 2003 | 8 | 0 - 1 | Round of 64 (1st rd) | Bob Huggins |
| 2004 | 4 | 1 - 1 | Round of 32 (2nd rd) | Bob Huggins |
| 2005 | 7 | 1 - 1 | Round of 32 (2nd rd) | Bob Huggins |
